By Sareen S. Gropper, Jack L. Smith, Timothy P. Carr
Present, accomplished, and designed to maximise readability of crucial options, longtime best-seller complex meals AND HUMAN METABOLISM provides its signature caliber content material in a student-friendly approach. The seventh variation keeps to set the normal in the course of the authors' skill to obviously and effectively clarify even the main advanced metabolic techniques and ideas, whereas staying at an undergraduate point. It supplies scholars an excellent knowing of digestion, absorption, and metabolism of fats, protein, and carbohydrates; examines the constructions and services of water-soluble and fat-soluble supplements -- together with their regulatory roles in metabolism; and offers info on diet and mineral meals assets, suggested intakes, deficiency, and toxicity. With complex nutrients AND HUMAN METABOLISM, seventh version, scholars might be prepared to proceed their reviews within the box of food.
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Additional info for Advanced Nutrition and Human Metabolism
The ER is classified as either rough (granular) or smooth (agranular). The granularity or lack of granularity is determined by the presence or absence of ribosomes. Rough endoplasmic reticulum (RER), so named because it is studded with ribosomes, abounds in cells where protein synthesis is a primary function. , the adrenal cortex and gonads) and in liver cells, which synthesize fat transport molecules (the lipoproteins). In skeletal muscle, SER is called sarcoplasmic reticulum and is the site of the calcium ion pump, a necessity for the contractile process.
Several conditions must be met for the enzyme to be suitably diagnostic: ■ ■ ■ ■ The enzyme must have a sufficiently high degree of organ or tissue specificity. Suppose an enzyme is widely distributed among organ or tissue systems. Although an abnormal increase in the activity of this enzyme in serum does indicate a pathological process with cellular damage, it cannot precisely identify the site of the damage. An example is lactate dehydrogenase (LDH). LDH activity is widely distributed among cells of the heart, liver, skeletal muscle, erythrocytes, platelets, and lymph nodes.
Protein designated Bcl-2 (B-cell lymphoma gene product) blocks the release of mitochondrial cytochrome c. By blocking the release of mitochondrial cytochrome c, Bcl-2 interferes with the apoptotic process. Bcl-2 is an integral membrane protein on the outer membrane of the mitochondrion. Two observations are relevant: ■ ■ Bcl-2 prevents the efflux of cytochrome c from the mitochondrion to the cytoplasmic matrix. Genetic overexpression of Bcl-2 prevents cells from undergoing apoptosis in response to various stimuli.
Advanced Nutrition and Human Metabolism by Sareen S. Gropper, Jack L. Smith, Timothy P. Carr